In vitro Carbonic Anhydrase Inhibitory Effects of The Extracts of Satureja cuneifolia

Carbonic anhydrases catalyze the interconversion between carbon dioxide and bicarbonate. anhydrase inhibition has therapeutic importance there are many drugs which use this mechanism. inhibitors used as diuretic, antiglaucoma, antitumor antiepileptic agents. As an alternative for synthetic chemicals with strong side effects, natural products have gained popularity in recent years. In study, Satureja cuneifolia, a medicinal plant folk medicine, was investigated its effects on carbonic I II enzymes. Four different extracts were obtained maceration method three solvents used. The results shown that methanol of cuneifolia strongest activity enzymes IC50 values 31 µg/mL hCA 12 II. Further purification analytical studies will be needed to obtain active molecules their potential pharma food industries.